Elevated IL-6 and Cardiovascular

IL-6 is a significant contributor to the development and progression of cardiovascular diseases, including atherosclerosis, heart failure, and hypertension. Elevated IL-6 levels drive chronic inflammation in blood vessels, promoting plaque formation and instability in atherosclerosis, which increases the risk of heart attacks and strokes. In heart failure, IL-6 exacerbates cardiac inflammation, weakening heart function and contributing to disease progression. Additionally, IL-6 is linked to endothelial dysfunction and vascular stiffness, playing a critical role in the development of hypertension. Targeting IL-6 through therapeutic and lifestyle interventions may help reduce inflammation, improve vascular health, and mitigate the risk of these cardiovascular conditions.